Did you know?
The Capra Science Immunization program™ is optimized for high antibody yields and low background.
Monoclonal antibody production
Antibody production from existing hybridoma or cell line
Monoclonal antibody development
Mouse monoclonal antibody development is generation of new hybridomas expressing antibodies to your antigen of interest. This procedure includes the steps of antigen generation (if needed), immunization program, cell fusion, screening of hybridoma, subcloning of positive hybridoma and purification of antibodies. Each step of the process is evaluated before you decide whether or not you want to commit to the next phase of development. We can also provide safety storage of your valuable hybridoma.
In the projects we undertake, we work in close and personal contact with our clients, to avoid misunderstanding and to enable a fruitful process to a successful end-product. Our work is based on a fee-for-service model. Hence, there will be no additional payments such as milestones, royalties or licence costs.
The technology of monoclonal antibody generation that we use has been used for several products that are being used in clinical diagnostics. Moreover, there are several approved drugs that have resulted from antibody humanization of developed mouse monoclonal antibodies using this technique. If you need to humanize your antibody at a later stage, we can assist you.
In the projects we undertake, we work in close and personal contact with our clients, to avoid misunderstanding and to enable a fruitful process to a successful end-product. Our work is based on a fee-for-service model. Hence, there will be no additional payments such as milestones, royalties or licence costs.
The technology of monoclonal antibody generation that we use has been used for several products that are being used in clinical diagnostics. Moreover, there are several approved drugs that have resulted from antibody humanization of developed mouse monoclonal antibodies using this technique. If you need to humanize your antibody at a later stage, we can assist you.
Antibody production from existing hybridoma
If you would like to produce antibodies from an already existing hybridoma, we can assist you. By shipping cells to us on dry ice, we can gently defrost the cells and passage them into volumes of your needs. We perform the purification of the media and deliver the pure antibodies in your choice of buffer and concentration. We routinely sign MTAs for these projects. Please contact us for a free quotation on your project.
Cloning and expression of antibodies
From the sequences of the variable regions of the Heavy and Light chain, we can clone them into expression vectors containing constant regions of your species and isoform of choice. After cloning, transfection of eucaryotic cells using transient gene expression is preformed, followed by harvesting and Immunoglobulin-purification.
If your antibody is not sequenced, we are able to assist you with this service.
Please contact us for a free quotation on your project.
If your antibody is not sequenced, we are able to assist you with this service.
Please contact us for a free quotation on your project.