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Antigen/protein production

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Would you like to use a peptide-conjugate, a whole protein or a subunit as antigen? If you don’t have the protein in-house, we can make it for you. 
We also have big experience in making antigens for phospho-specific or acytelation-specific antibody development.
We use the following techniques for antigen development:

Peptide synthesis and conjugation
Peptide synthesis and conjugation to carrier protein for peptide-specific antibodies, is today the most popular way of generating an antigen. We can help you pin-point areas of the the protein that is suitable for antibody generation, using our peptide design service.

Recombinant protein generation
We can offer gene synthesis and transient gene expression for the production of recombinant proteins in eukaryote or prokaryote cells. 

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Fab2 or Fab fragment generation

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When making an anti-drug antibody assay,  antibodies specific to the variable regions of your antibody needs to be generated.

We can assist you with generating and purifying Fab2 or Fab fragments of antibodies. The purified Fab-fragments will be used as antigen to generate antiserum, which in turn can be affinity purified for your assay. 

More info regarding ADA  development.