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Llama antibodies show great potential

5/18/2018

 
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Image from: https://doi.org/10.1016/j.bbapap.2014.08.016
 
Antibodies derived from llamas, called nanobodies, comprise only a small part (a single domain) of conventional antibodies, yet possess full antigen-binding capacity. These nanobodies have shown great potential both as structural tools and as therapeutic agents in a number of diseases caused by protein dysfunction.

A study by Dr. Erwin De Genst and Dr. Marija Iljina reports that llama-derived nanobodies – essentially miniature antibodies – might find therapeutic application in Parkinson’s disease. The nanobodies can bind to harmful protein clumps in the brain, called oligomers, to neutralize toxicity and help prevent cell death. Furthermore, they found that the nanobodies are able to slow down the oligomer’s aggregation reaction.

We are happy to announce that in the near future, Capra Science farm will be housing llamas for development of nanobodies. More information will follow shortly.

The source of the study: https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0390-6

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    "As you can see, we are not very good at posting news here on a regular bases, as we are very busy spending all our time  generating important antibodies for our customers and taking care of our precious goats, rabbits, alpacas, hens and mice."
    - Lovisa Hessle Bergman, Managing Director




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